Guide to the Markets
Guide to the Markets
Equities Top 5 Gainers & LosersMarket CalendarAdvance-Decline LineIndex Performance ComparisonUS Large Caps Sector PerformanceVolume TrendsRates & Credit SpreadsCBOE Put/Call RatioCBOE Volatility Index (VIX)
US Large Caps at Inflection PointsEPS Growth DecompositionTop 10: Weight & ValuationMagnificent 7Annual Returns and Intra-Year DeclinesReturns and Valuations by StyleFactorsImpact of Missing the Best and Worst DaysEquity Correlations
10-Year Treasury YieldTreasury Yield Curve Slope (2s10s)Treasury Yield CurveTreasury Yield Curve — This Year vs Last YearTreasury Yield Changes (Period over Period)Credit Spreads (High Yield & Investment Grade)Inflation BreakevensReal vs. Nominal YieldPolicy Rate (Fed Funds & SOFR)
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Notable Insider PurchasesHistorical Data CoverageIdentifier Spot ChecksData Gap Analysis
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Equities Top 5 Gainers & Losers

Today's biggest movers in the US Large Caps — the top 5 gainers and top 5 losers by percentage change.

Equities Top 5 Gainers & Losers — as of 2026-09-25
SymbolOpenIndustryCloseVolume% ChangeDateCompany
LONA5.19BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)3.25342,950-34.872026-09-25LeonaBio, Inc. Common Stock
GSNR18.25—12.15183,371-36.052026-09-25GRAYSCALE NEAR TRUST
WYY10.93SERVICES-COMPUTER INTEGRATED SYSTEMS DESIGN5.473,890,566-50.592026-09-25WidePoint Corporation
IPEX7.11BLANK CHECKS3.16728,994-57.752026-09-25Inflection Point Acquisition Corp. V Class A Ordinary Shares
AXG1.21BLANK CHECKS0.298,180,816-84.622026-09-25Solowin Holdings Class A Ordinary Share
APUS8.32PHARMACEUTICAL PREPARATIONS7.2536,723,74347.362026-09-25Apimeds Pharmaceuticals US, Inc.
TDIC1.99SERVICES-MANAGEMENT SERVICES3.1637,292,37960.412026-09-25Dreamland Limited Class A Ordinary Shares
AIFF1.71SERVICES-PREPACKAGED SOFTWARE2.01139,374,71268.912026-09-25Firefly Neuroscience, Inc. Common Stock
INLF6.25LIFE INSURANCE5.148,759,47772.882026-09-25INLIF LIMITED Class A Ordinary Shares
MGLD1.95FINANCE SERVICES1.9315,458,29893.022026-09-25The Marygold Companies, Inc.

Source: Akyla · akyla.ai